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Post by melody on Nov 8, 2012 13:15:52 GMT -5
Pennsylvania Department of Agriculture expands chronic wasting disease quarantine list to include 27 deer farms in 16 countiesNovember 08, 2012 blog.pennlive.com/pa-sportsman/2012/11/pennsylvania_department_of_agriculture_expands_chronic_wasting_disease_quarantine_list_to_include_27.htmlAgain this week, the state Department of Agriculture has expanded the list of Pennsylvania deer farms under quarantine because of potential exposure of deer on those farms to deer already confirmed to have been infected with chronic wasting disease. The list of deer farms quarantined by Ag because of contact with deer from a New Oxford enclosure, where CWD was first confirmed, has grown to 27 farms in 16 counties. View full sizeThe Associated Press, 2007A pair of white tail deer nuzzle each other in the woods outside Zelienople, Pa. A doe and a buck from an enclosure at 1491 New Chester Road, New Oxford, have been confirmed as having CWD, an always fatal disease of the brain in cervids like deer, elk and moose. The 3.5-year-old doe was Pennsylvania's first confirmed case of CWD. After she died in the enclosure on Oct 4, she was tested for the disease and confirmed on Oct. 10. That triggered the state's CWD response plan for action by agencies including Agriculture and the Pennsylvania Game Commission. Part of the plan called for the "depopulation" of all deer on the farm of the initial CWD confirmation, which is now referred to as "the index farm," according to Mathew Meals, deputy secretary of the state Department of Agriculture. The other seven deer killed in the enclosure Oct. 18 by staff from Ag and agents from the USDA's Wildlife Services for CWD testing did not have the disease, according to Ag. There is no live-test available for suspect animals. However, a ninth deer, a doe known as Pink 23, escaped from the enclosure while the agents were culling the herd for testing. She remains free in the wild. The buck was confirmed to have had CWD on Nov. 7. In addition to "the index farm at New Oxford, three other farms were initially quarantined: Bryan Rutters, Rut Acres, 61 Pickett Road and 295 Bremer Road, Dover; and Mike Schilling, Lost Mountain Whitetails, 6464 Jacks Hollow Road, Williamsport. The quarantine list grow to a dozen farms last week: William Noll, Noll's Whitetails, 8029 Molly Pitcher Highway, Shippensburg; Harry Eichelberger, Bud's Place, 5032 Eichelberger Lane, Spring Grove; Matthew Anthony, Anthony Whitetail Ranch, 830 Woodel Road, Grampian; Carl Rockey, 1305 New Chester Road, New Oxford; Troy Luckenbaugh, Harvest Acres, 170 Dicks Dam Road, New Oxford; Zachary N. Nelson, Cole Creek Whitetails, 80 Bordell Cross Road, Smethport; Dwain Koser and Bradly Kauffman, Bradly/Koser's Whitetail Trophy II, 1309 Private Oak Lane, Shippensburg; and Dwain Koser, Koser's Trophy Whitetails, 46 Springfield Road, Shippensburg. And, this week Ag placed another 15 deer farms under quarantine: Garth Book, Book Whitetails, 240 Prospect Road, Sugarloaf; John Ficks III, Nittany Mountain Hunting Preserve, 2980 Millers Bottom Road, New Columbia; John Ficks III, Fick's Whitetails; Kenneth Erway, Spring Hollow Farms Pen 1 (Whitetail Country), 5914 Route 287, Wellsboro; Larry Pittenger, Thunder Valley Whitetails, 4733 Warrensville Road, Montoursville; Ronald Truitt, 1135 Carriage Road, Fairmont City; John McAdam, Endless Mountain Whitetails, 953 Old Bernice Road, Mildred; Josh Blyler, J & L Whitetails, 7 Scenic Road, Klingerstown; Denis Beachel, Power View Whitetails, 390 Fairview Road, Danville; Travis Rhodes, Freedom Whitetails, 694 Johnstown Road, East Freedom; Mathew Nelson, Nelson's Whitetails, 190 Nelson Lane, East Freedom; Jeff Trent, 483 Big Hill Road, Gardners; Noah Wonderling, Hollow Tree Whitetails, 665 Megnin Road, Limestone; Stacy Fry, Pipeline Ridge, 1433 Weisterwoods Rd, Muncy; Rocky Reed, North Mountain Outfitters, 1276 Logue Hill Rd, Hughesville; Rocky Reed, 2523 US Highway 220, Pennsdale; and Gordon Trimer, 4794 Trimers Rd, Alexandria. At the initial CWD-response public meeting Oct. 17, Assistant State Veterinarian David Griswold estimated that the impact of the one CWD-infected deer could hit a hundred farms across the state because "deer farmers in Pennsylvania tend to move a lot of deer." Ag is continuing its "trace out" process to find all possible connections to the CWD deer, according to Samantha Krepps, spokesman for the department of agriculture. According to Ag, more than 1,100 farms across the state are home to more than 23,000 cervids.
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Post by dennyf on Nov 8, 2012 16:22:45 GMT -5
Last month they estimated it was 25,000, now it's 23,000? Is that how many have "escaped" in the past 30 days?
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Post by Deleted on Nov 8, 2012 17:33:15 GMT -5
At the very least, ther should be two fences around these places the fence to keep the deer in and another ten feet from the first one to keep wild deer away from the first fence.
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Post by melody on Nov 9, 2012 10:38:07 GMT -5
Wildlife officials hold public meeting on chronic wasting diseaseNov 08, 2012 By Dan Carrigan www.abc27.com/story/20049538/wildlife-officials-hold-chronic-wasting-public-meetingYORK, Pa. (WHTM) - Deer farmers, hunters and concerned residents showed up for a public meeting hosted by state wildlife officials at the York Fairgrounds Thursday night, armed with questions about chronic wasting disease. Representatives from the Pennsylvania Game Commission and the Department of Agriculture were on hand to give a presentation and answer any questions. The crowd had plenty of concerns. One man asked about the deer that escaped the quarantined New Oxford farm, the same place where cases of chronic wasting disease were already found. Officials said they are searching high and low, day and night for the doe that got away. They did not know if it had chronic wasting disease. However, one official pointed out that 10 deer were at the farm and only two had CWD. "They said that deer is out there and it's running around. It's possibly in my woods behind my home and I want to know what's being done about that," one man said. Chronic wasting disease is fatal in deer, elk and moose, but the U.S. Centers for Disease Control and Prevention has said there is no evidence the illness can be transmitted to humans or livestock. The Agriculture Department has quarantined the farm and 27 others in 16 counties that are associated with the positive samples. Deer cannot be moved on or off quarantined properties. The Pennsylvania Game Commission has established a disease management area surrounding the farm where the deer tested positive. As part of that plan, hunters may not move high-risk deer parts out of the area, including parts of the head and spinal column. Hunters who harvest a deer within the disease management area during the two-week firearms deer season from November 26 to December 8 are required to bring their deer to a mandatory check station so samples can be collected for testing. For the convenience of hunters, all cooperating deer processors within the disease management area will be considered check stations. The Game Commission will be gathering samples from hunter-killed deer at those processors. A list of cooperating deer processors and taxidermists will be announced and posted on the commission's website. Hunters who harvest a deer within the management area and who process their own deer, or who would like to take their deer to a processor or taxidermist outside of the management area, can visit the Game Commission operated check station at the agency's maintenance building on State Game Land 249, at 1070 Lake Meade Road in East Berlin. Game Commission check station hours during the two-week rifle deer season are from 8 a.m. to 8 p.m., Monday through Saturday, but will remain open as needed. The check station will be closed on Sunday, December 2. Deer harvested outside of the management area will not be eligible for testing at the check station. However, hunters may get their deer tested by the Department of Agriculture's Veterinary Laboratory in Harrisburg, for a fee. Interested hunters should call 717-787-8808. Sources Include: Pa. Department of Agriculture, Pa. Game Commission
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Post by dennyf on Nov 9, 2012 10:44:20 GMT -5
"Officials said they are searching high and low, day and night for the doe that got away. They did not know if it had chronic wasting disease. However, one official pointed out that 10 deer were at the farm and only two had CWD." Apparently they don't often deal in percentages over there? If "only" two out of ten deer in the wild tested positive for CWD, imagine the chaos here.
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Post by melody on Nov 9, 2012 10:54:42 GMT -5
York County hunters express concern, ask questions about chronic wasting diseaseOfficials say there's no need to panic, but chronic wasting disease is tough to eradicate. By JIM SEIP Daily Record/Sunday News 11/09/2012 www.ydr.com/local/ci_21961484/york-county-hunters-express-concern-ask-questions-aboutNo one is calling it a doomsday scenario for Pennsylvania's wild deer herd. Not yet at least. But the first presence of chronic wasting disease from a deer in the state of Pennsylvania has created concern for hunters in York and Adams counties. Two captive deer from New Oxford have tested positive for the disease. More than 100 hunters listened to a near-hour long presentation by the Pennsylvania Game Commission on CWD at the York Expo Center Thursday night. Hours after the meeting began, hunters continued to ask questions about the disease and what type of impact it would have on this year's rifle season. Read More: www.ydr.com/local/ci_21961484/york-county-hunters-express-concern-ask-questions-aboutThere's a map of the quarantined farm locations as well. Hunters are still blaming the PGC for a lack of information, and for not getting the fence back up. Someone needs to aks the question publicly at one of these meetings about just who is in control of getting that fence back up and not let them sidestep the answer that it is Ag.
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Post by flounder on Nov 9, 2012 11:33:30 GMT -5
Wildlife officials hold public meeting on chronic wasting diseaseNov 08, 2012 By Dan Carrigan www.abc27.com/story/20049538/wildlife-officials-hold-chronic-wasting-public-meetingYORK, Pa. (WHTM) - Deer farmers, hunters and concerned residents showed up for a public meeting hosted by state wildlife officials at the York Fairgrounds Thursday night, armed with questions about chronic wasting disease. snip... Chronic wasting disease is fatal in deer, elk and moose, but the U.S. Centers for Disease Control and Prevention has said there is no evidence the illness can be transmitted to humans or livestock. snip... Sources Include: Pa. Department of Agriculture, Pa. Game Commission > but the U.S. Centers for Disease Control and Prevention has said there is no evidence the illness can be transmitted to humans or livestock. that statement is a red herring, or simply not completely true, take your pick, depending what you consider as evidence. let’s evaluate this, shall we, and you be the judge... Friday, November 09, 2012 Chronic Wasting Disease CWD in cervidae and transmission to other species chronic-wasting-disease.blogspot.com/2012/11/chronic-wasting-disease-cwd-in-cervidae.html kind regards, terry
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Post by Deleted on Nov 10, 2012 8:45:27 GMT -5
I share a concern for the "unknown" effects of this and possibly other diseases. But your links have shed no light on the existence of any proof positive connections to human transmission..................? There is an awful lot of "don't believe what you read," but woefully little, if any, of --- "here is proof."
Sorry, not being a conspiracy theorist, I really have to stick with the universities, and agencies, public and private who work on this. If I believed in a moral deficit in those studies --- I'd guess that many of them would love to find a link so they could work that angle for profit.
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Post by galthatfishes on Nov 10, 2012 9:42:14 GMT -5
Bob;
Here is what the CDC says: Transmission CWD can be highly transmissible within deer and elk populations. The mode of transmission is not fully understood, but evidence supports the possibility that the disease is spread through direct animal-to-animal contact or as a result of indirect exposure to prions in the environment (e.g., in contaminated feed and water sources). Several epidemiologic studies provide evidence that, to date, CWD has not been transmitted to humans. Additionally, routine surveillance has not shown any increase in the incidence of Creutzfeldt-Jakob disease in Colorado or Wyoming.
Specific studies have begun that focus on identifying human prion disease in a population that is at increased risk for exposure to potentially CWD-infected deer or elk meat. Because of the long time between exposure to CWD and the development of disease, many years of continued follow-up are required to be able to say what the risk, if any, of CWD is to humans.
Simply, there is no conclusive evidence showing that the prion in deer can jump the species barrier; but there IS conclusive evidence that it has jumped the species barrier when its a BSE (Mad cow).
CWD in Colorado's farmed deer herd where CWD was first contracted, there were sheep with scrapie in that field. They killed all of the sheep and nearly 2 decades later it was stocked with deer. They believe the prion jumped the barrier at that point.
Just some history on why people are concerned.
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Post by flounder on Nov 10, 2012 12:42:49 GMT -5
I share a concern for the "unknown" effects of this and possibly other diseases. But your links have shed no light on the existence of any proof positive connections to human transmission..................? There is an awful lot of "don't believe what you read," but woefully little, if any, of --- "here is proof." Sorry, not being a conspiracy theorist, I really have to stick with the universities, and agencies, public and private who work on this. If I believed in a moral deficit in those studies --- I'd guess that many of them would love to find a link so they could work that angle for profit. hello bowbum, i kindly disagree with the profit angle. i guess one has to make there own mind up, on the studies to date. we all will not read or interpret them the same. however, a few things you might want to consider when feeding your family suspect CWD positive deer, and that would be any cervid, due to sub-clinical nature, and understanding, i don't care what you eat. 1. the USA CJD surveillance unit is about as good at finding CJD of any strain, as the USDA is of finding BSE in cattle. 2. cwd transmission studies on humans is illegal. never will happen. 3. cwd to human transmission, could possibly be one of the many sub-strains of the sporadic CJD. the USA has new strains of sporadic CJD of UNKNOWN TYPE. all sporadic CJD is, is CJD TSE from UNKNOWN route and source. 4. cwd transmits to squirrel monkey orally. Regardless, the finding that a primate is orally susceptible to CWD is of concern. wwwnc.cdc.gov/eid/article/18/3/11-0685_article.htm i remember one of the top prion gods saying all the correct things in public, but behind closed doors, and in confidence, he stated ; 5. A positive result from a chimpanzee challenged severely would likely create alarm in some circles even if the result could not be interpreted for man. I have a view that all these agents could be transmitted provided a large enough dose by appropriate routes was given and the animals kept long enough. Until the mechanisms of the species barrier are more clearly understood it might be best to retain that hypothesis. 6. A negative result would take a lifetime to determine but that would be a shorter period than might be available for human exposure and it would still not answer the question regarding mans' susceptibility. In the meantime no doubt the negativity would be used defensively. It would however be counterproductive if the experiment finally became positive. We may learn more about public reactions following next Monday' s meeting. R. Bradley 23 September 1990 CVO (+Mr Wells' comments) Dr T W A Little Dr B J Shreeve 90/9.23/1.1. collections.europarchive.org/tna/20080102222950/http://www.bseinquiry.gov.uk/files/yb/1990/09/23001001.pdf scrapie-usa.blogspot.com/2011/02/in-confidence-scrapie-transmission-to.html 2011-1012 Recently, PrPTSE and its proteinaceous seeding activity could be directly demonstrated, for the first time, in skeletal muscles of CWD-infected cervids.10 The animals examined in this study were farmed and free-ranging WTD for which no clinical signs of CWD had been recognized. However, they had been officially confirmed positive for CWD based on the detection of PrPTSE in brain tissue or lymph nodes and were thus apparently in a state of pre or subclinical infection. Muscles from such clinically inconspicuous carrier animals appear more likely to enter the human food chain than meat from cervids that show symptoms of CWD. Whether this may provide a relevant mode for the inadvertent foodborne transmission of CWD prions is still unclear. Yet, the presence and seeding activity of PrPTSE in skeletal muscles of pre- or subclinically infected WTD reinforced the need to comprehensively assess whether humans are susceptible to zoonotic CWD infections. snip... Transmissibility to humans The current state of epidemiological research suggests a rather robust barrier for the transmission of CWD to humans. Particularly, the surveillance of human prion diseases in areas with a long history of endemic CWD such as Colorado and Wyoming did not reveal evidence for zoonotic transmissions of the disease to cervid hunters or consumers of meat from elk and deer.6,11 However, as discussed by Belay et al.,6 the intensity of human exposure to CWD prions may increase due to a further spread and rising prevalence of the disease in cervids. Therefore, and with the generally long latency periods of human prion diseases in mind, previous epidemiological findings cannot be readily extrapolated. Until recently, experimental studies that pursued biochemical approaches or used transgenic mice to ascertain the susceptibility of humans to CWD infections consistently seemed to corroborate current epidemiological findings: CWD-infected cervid brain tissue did not seed the conversion of PrPC 133 into PrPres in PMCA assays using brain homogenate from macaques or transgenic mice expressing human PrPC as test substrate12 , and transgenic mice overexpressing human PrPC were resistant to infection after intracerebral challenge with CWD prions from mule deer.13 However, a study published by Barria et al.14 in March 2011 found that cervid PrPTSE can seed the conversion of human PrPC into PrPres by PMCA when the CWD agent has been previously passaged in vitro or in vivo. Specifically, this was demonstrated for CWD prions from naturally affected mule deer either passaged by serial PMCA using deer PrPC as conversion substrate or in transgenic mice expressing cervid PrPC. The authors of this study pointed out that CWD prions may undergo a gradual process of change and adaptation via successive passages in the cervid population. They concluded that the reported findings, if corroborated by infectivity assays, may imply “that CWD prions have the potential to infect humans and that this ability progressively increases with CWD spreading”. snip... edoc.rki.de/oa/articles/reYkQuqqds4M/PDF/20oNZTyNNXg.pdf Volume 18, Number 3—March 2012 Samuel E. Saunders1, Shannon L. Bartelt-Hunt, and Jason C. Bartz Author affiliations: University of Nebraska-Lincoln, Omaha, Nebraska, USA (S.E. Saunders, S.L. Bartelt-Hunt); Creighton University, Omaha (J.C. Bartz) Synopsis Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease snip... Most epidemiologic studies and experimental work have suggested that the potential for CWD transmission to humans is low, and such transmission has not been documented through ongoing surveillance (2,3). In vitro prion replication assays report a relatively low efficiency of CWD PrPSc-directed conversion of human PrPc to PrPSc (30), and transgenic mice overexpressing human PrPc are resistant to CWD infection (31); these findings indicate low zoonotic potential. However, squirrel monkeys are susceptible to CWD by intracerebral and oral inoculation (32). Cynomolgus macaques, which are evolutionarily closer to humans than squirrel monkeys, are resistant to CWD infection (32). Regardless, the finding that a primate is orally susceptible to CWD is of concern. snip... Intraspecies and interspecies passage of the CWD agent may also increase the risk for zoonotic CWD transmission. The CWD prion agent is undergoing serial passage naturally as the disease continues to emerge. In vitro and in vivo intraspecies transmission of the CWD agent yields PrPSc with an increased capacity to convert human PrPc to PrPSc (30). Interspecies prion transmission can alter CWD host range (38) and yield multiple novel prion strains (3,28). The potential for interspecies CWD transmission (by cohabitating mammals) will only increase as the disease spreads and CWD prions continue to be shed into the environment. This environmental passage itself may alter CWD prions or exert selective pressures on CWD strain mixtures by interactions with soil, which are known to vary with prion strain (25), or exposure to environmental or gut degradation. Given that prion disease in humans can be difficult to diagnose and the asymptomatic incubation period can last decades, continued research, epidemiologic surveillance, and caution in handling risky material remain prudent as CWD continues to spread and the opportunity for interspecies transmission increases. Otherwise, similar to what occurred in the United Kingdom after detection of variant CJD and its subsequent link to BSE, years of prevention could be lost if zoonotic transmission of CWD is subsequently identified,... snip... wwwnc.cdc.gov/eid/article/18/3/11-0685_article.htm chronic-wasting-disease.blogspot.com/2012/11/chronic-wasting-disease-cwd-in-cervidae.html CJD9/10022 October 1994 Mr R.N. Elmhirst Chairman British Deer Farmers Association Holly Lodge Spencers Lane BerksWell Coventry CV7 7BZ Dear Mr Elmhirst, CREUTZFELDT-JAKOB DISEASE (CJD) SURVEILLANCE UNIT REPORT Thank you for your recent letter concerning the publication of the third annual report from the CJD Surveillance Unit. I am sorry that you are dissatisfied with the way in which this report was published. The Surveillance Unit is a completely independant outside body and the Department of Health is committed to publishing their reports as soon as they become available. In the circumstances it is not the practice to circulate the report for comment since the findings of the report would not be amended. In future we can ensure that the British Deer Farmers Association receives a copy of the report in advance of publication. The Chief Medical Officer has undertaken to keep the public fully informed of the results of any research in respect of CJD. This report was entirely the work of the unit and was produced completely independantly of the the Department. The statistical results reqarding the consumption of venison was put into perspective in the body of the report and was not mentioned at all in the press release. Media attention regarding this report was low key but gave a realistic presentation of the statistical findings of the Unit. This approach to publication was successful in that consumption of venison was highlighted only once by the media ie. in the News at one television proqramme. I believe that a further statement about the report, or indeed statistical links between CJD and consumption of venison, would increase, and quite possibly give damaging credence, to the whole issue. From the low key media reports of which I am aware it seems unlikely that venison consumption will suffer adversely, if at all. web.archive.org/web/20030511010117/http://www.bseinquiry.gov.uk/files/yb/1994/10/00003001.pdf PPo3-7: Prion Transmission from Cervids to Humans is Strain-dependent Qingzhong Kong, Shenghai Huang,*Fusong Chen, Michael Payne, Pierluigi Gambetti and Liuting Qing Department of Pathology; Case western Reserve University; Cleveland, OH USA *Current address: Nursing Informatics; Memorial Sloan-Kettering Cancer Center; New York, NY USA Key words: CWD, strain, human transmission Chronic wasting disease (CWD) is a widespread prion disease in cervids (deer and elk) in North America where significant human exposure to CWD is likely and zoonotic transmission of CWD is a concern. Current evidence indicates a strong barrier for transmission of the classical CWD strain to humans with the PrP-129MM genotype. A few recent reports suggest the presence of two or more CWD strains. What remain unknown is whether individuals with the PrP-129VV/MV genotypes are also resistant to the classical CWD strain and whether humans are resistant to all natural or adapted cervid prion strains. Here we report that a human prion strain that had adopted the cervid prion protein (PrP) sequence through passage in cervidized transgenic mice efficiently infected transgenic mice expressing human PrP, indicating that the species barrier from cervid to humans is prion strain-dependent and humans can be vulnerable to novel cervid prion strains. Preliminary results on CWD transmission in transgenic mice expressing human PrP-129V will also be discussed. Acknowledgement Supported by NINDS NS052319 and NIA AG14359. PPo2-7: Biochemical and Biophysical Characterization of Different CWD Isolates Martin L. Daus and Michael Beekes Robert Koch Institute; Berlin, Germany Key words: CWD, strains, FT-IR, AFM Chronic wasting disease (CWD) is one of three naturally occurring forms of prion disease. The other two are Creutzfeldt-Jakob disease in humans and scrapie in sheep. CWD is contagious and affects captive as well as free ranging cervids. As long as there is no definite answer of whether CWD can breach the species barrier to humans precautionary measures especially for the protection of consumers need to be considered. In principle, different strains of CWD may be associated with different risks of transmission to humans. Sophisticated strain differentiation as accomplished for other prion diseases has not yet been established for CWD. However, several different findings indicate that there exists more than one strain of CWD agent in cervids. We have analysed a set of CWD isolates from white-tailed deer and could detect at least two biochemically different forms of disease-associated prion protein PrPTSE. Limited proteolysis with different concentrations of proteinase K and/or after exposure of PrPTSE to different pH-values or concentrations of Guanidinium hydrochloride resulted in distinct isolate-specific digestion patterns. Our CWD isolates were also examined in protein misfolding cyclic amplification studies. This showed different conversion activities for those isolates that had displayed significantly different sensitivities to limited proteolysis by PK in the biochemical experiments described above. We further applied Fourier transform infrared spectroscopy in combination with atomic force microscopy. This confirmed structural differences in the PrPTSE of at least two disinct CWD isolates. The data presented here substantiate and expand previous reports on the existence of different CWD strains. www.prion2010.org/bilder/prion_2010_program_latest_w_posters_4_.pdf?139&PHPSESSID=a30a38202cfec579000b77af81be3099 chronic-wasting-disease.blogspot.com/2010/09/cwd-prion-2010.html OR-12: Chronic wasting disease transmission and pathogenesis in cervid and non-cervid Species Edward A. Hoover, Candace K. Mathiason, Nicholas J. Haley, Timothy D. Kurt, Davis M. Seelig, Nathaniel D. Denkers, Amy V. Nalls, Mark D. Zabel, and Glenn C. Telling Prion Research Program, Department of Microbiology, Immunology, and Pathology; Colorado State University; Fort Collins, CO USA Since its recognition as a TSE in the late 1970s, chronic wasting disease (CWD) of cervids has been distinguished by its facile spread and is now recognized in 18 states, 2 Canadian provinces, and South Korea. The efficient horizontal spread of CWD reflects a prion/host relationship that facilitates efficient mucosal uptake, peripheral lymphoid amplification, and dissemination by exploiting excretory tissues and their products, helping to establish indirect/environmental and well as direct (e.g., salivary) transmission. Recent studies from our group also support the likelihood of early life mother to offspring and aerosol CWD prion transmission. Studies of cervid CWD exposure by natural routes indicate that incubation period for detection of overt infection, while still uncertain, may be much longer than originally thought. Several non-cervid species can be infected by CWD experimentally (e.g., ferrets, voles, cats) with consequent species-specific disease phenotypes. The species-adapted prions so generated can be transmitted by mucosal, i.e., more natural, routes. Whether non-cervid species sympatric with deer/elk can be infected in nature, however, remains unknown. In vitro CWD prion amplification studies, in particular sPMCA, can foreshadow in vivo susceptibility and suggest the importance of the PrPC rigid loop region in species barrier permissiveness. Trans-species CWD amplification appears to broaden the host range/strain characteristics of the resultant prions. The origins of CWD remain unknown, however, the existence of multiple CWD prion strains/ quasi-species, the mechanisms of prion shedding/dissemination, and the relationship between sheep scrapie and CWD merit further investigation. snip... The discovery of previously unrecognized prion diseases in both humans and animals (i.e., Nor98 in small ruminants) demonstrates that the range of prion diseases might be wider than expected and raises crucial questions about the epidemiology and strain properties of these new forms. We are investigating this latter issue by molecular and biological comparison of VPSPr, GSS and Nor98. snip... prion2012 oral presentation... PO-049: Different transmission patterns in two genetic lines of bank voles suggest the presence of multiple strain variants in Nor98 isolates www.landesbioscience.com/journals/prion/03-Prion6-2-Transmission-and-strains.pdf you must remember, science has now shown that it is very likely that CWD in cervids, emerged from scrapie in sheep and goats. there are over 25 different strains of typical sheep scrapie, with atypical scrapie types growing, if you consider the CH1641 type scrapie an atypical strain, as the Nor-98 atypical strain, which there from the list of strains grows as well. how many of strains of CWD are there now, and how many will there be ? only God knows that. ... Friday, November 09, 2012 Chronic Wasting Disease CWD in cervidae and transmission to other species chronic-wasting-disease.blogspot.com/2012/11/chronic-wasting-disease-cwd-in-cervidae.html again, one has to make ones own mind up when assessing risk assessment on the TSE Prion disease, for them and their family. a long incubating disease, one that once clinical, the TSE prion agent is 100% fatal. I think everyone when making this decision (consumer and policy makers), should have all the science available. a lot of the times, this does not happen. good luck. ... kind regards, terry
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Post by galthatfishes on Nov 10, 2012 13:31:07 GMT -5
Thanks Terry. Long but worth the read.
Simply; all of the above says there are several strains of CJS (the human TSE) now.
Its crossed species barriers before; and there are several varient strains of TSE which are mainly believed to have started with scrapie in sheep and goats. Cattle is a BSE which DOES transverse the species barrier. The deer version of CWD is not yet PROVED to have jumped the barrier, but because of the extended incubation in humans, its something we may not realize for decades if it ever does cross over.
They have been able to transfer one of the forms of CWD into a monkey that is distantly related to us. Our closer primate relatives have not yet shown to contract; but it could be as close as one mutation away.
Bottom line, don't eat infected meat unless you want to be the himan test dummy for mad deer disease.
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Post by Deleted on Nov 11, 2012 9:37:11 GMT -5
Terry, there's a whole bunch of "could possibly" in most of those snips.
I also think most statements, such as below, could be applied to cancer research, polio or other "thought to be" non transmittable. Quote: "I have a view that all these agents could be transmitted provided a large enough dose by appropriate routes was given and the animals kept long enough."
Also, I think it very pragmatic to believe that researchers would absolutely love to find the link, if there is one, in order to champion treatment and thus --- profit!
There is nothing unethical about wanting to be a leader in treatment of a dreaded disease.
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Post by flounder on Nov 11, 2012 14:32:10 GMT -5
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Post by melody on Nov 13, 2012 10:31:21 GMT -5
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Post by galthatfishes on Nov 13, 2012 21:22:17 GMT -5
blog.pennlive.com/pa-sportsman/2012/11/another_deer_linked_to_site_of_pennsylvanias_first_confirmed_case_of_chronic_wasting_disease_is_repo.htmlAnother deer linked to site of Pennsylvania's first confirmed case of chronic wasting disease is reported as escaped into the wildPublished: Tuesday, November 13, 2012 Another deer linked to the captive herd in New Oxford, Adams County, where Pennsylvania saw its first two confirmed cases of the deadly chronic wasting disease over the past month, has been reported as escaped from a deer farm in Alexandria, Huntingdon County. The escapee – designated as Purple 4 in the state's deer farming industry – escaped from the Gordon Trimer enclosure at 4794 Trimers Rd, Alexandria, according to Mathew Meals, deputy secretary of the state Department of Agriculture. More...
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Post by dennyf on Nov 13, 2012 21:31:27 GMT -5
Interesting tidbit, relative to the post about the guy offering a reward for an escaped deer: "Another deer linked to the captive herd in New Oxford, Adams County, where Pennsylvania saw its first two confirmed cases of the deadly chronic wasting disease over the past month, has been reported as escaped from a deer farm in Alexandria, Huntingdon County. The escapee – designated as Purple 4 in the state's deer farming industry – escaped from the Gordon Trimer enclosure at 4794 Trimers Rd, Alexandria, according to Mathew Meals, deputy secretary of the state Department of Agriculture. He said prior to its escape into the wild "several months ago," the deer was sold or otherwise transferred to Trimer from the Freedom Whitetails facility of Travis Rhodes at 694 Johnstown Road, East Freedom. Rhodes had acquired the deer from the Ronald Rutters herd at 1491 New Chester Road, New Oxford. Meals noted that the Alexandria operation did not have the required license for operating a deer farm from Ag and the situation there is "under investigation by the department." Now we know why. That post, 11/2/12: Announcement: There was a Whitetail doe escaped in the Alexandria-Huntingdon area. I am offering a reward for anyone that can hunt this doe. She has a purple 4 ear tag and a state ear tag in the other ear if found I will pay 200 to the hunter that can call me with the ear tag number and go from there my number is 814-312-7833. Please spread the word in the area. Thank you Freedom Whitetails Call or text with any questions. No questions will be asked about the harvest of the doe
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Post by flounder on Nov 14, 2012 19:07:36 GMT -5
PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO LOUISIANA Got a private email. snip...as follows ; I would pass along a story. Nothing official has come out, but I have inside sources with multiple federal and state agencies in LA. But a deer or multiple deer, not sure which, from a CWD positive pen in PA was moved to a pen somewhere around Lake Charles, LA. The deer may have been moved to at least one other pen in LA, and possible one in MS as well, but no one really knows. There are supposedly 150 deer at the pen in Lake Charles that were quarentined and killed and they are now trying to figure out how and where to dispose of the carcasses. Everything is very sketchy and grey right now, but it is now possible that CWD could have spread to 1 or 2 more states. We shall see in the next few weeks if any kind of official press release comes out...end Read more: www.pfsc.proboards.com/index.cgi?action=display&board=disease&thread=583&page=1#ixzz2CDyJGlfYwww.pfsc.proboards.com/index.cgi?action=display&board=disease&thread=583&page=1 so, I gave the Pa dept of ag a call. this is the kind reply I got. ...tss From: xxxxxxxxx xxxxxx Sent: Wednesday, November 14, 2012 4:03 PM To: 'Flounder9@verizon.net' Subject: Deer information Terry - The animal moved on a certificate of veterinary inspection prior to the discovery of the positive CWD herd in Pennsylvania. Louisiana animal health authorities are investigating the movement of this deer that was epidemiologically linked to the index Pennsylvania herd, into their state. We are awaiting their response. Since the announcement of CWD positives in Pennsylvania there are no states permitting the movement of imported Pennsylvania deer and the Department of Agriculture is not permitting the movement of any deer into the commonwealth. -xxxxxx snip... Pennsylvania Department of Agriculture | Press Office 2301 North Cameron Street | Hbg PA 17110 Phone: 717.787.5085 | Fax: 717.787.1039 www.agriculture.state.pa.us ==================== I thank the Dept of Penn Ag for that kind reply and information. I pray that CWD has not been transported to Louisiana from Pennsylvania, via the great escape of CWD 2012 into Pennsylvania from captive game farming. ...tss Tuesday, November 13, 2012 PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD chronic-wasting-disease.blogspot.com/2012/11/pennsylvania-2012-great-escape-of-cwd.html TSS Wednesday, November 14, 2012 PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO LOUISIANA chronic-wasting-disease.blogspot.com/2012/11/pennsylvania-2012-great-escape-of-cwd_14.html
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Post by flounder on Nov 15, 2012 13:19:59 GMT -5
TALK about a mess. here is the latest on Louisiana, PA deer. got an email from the Son, of the Game Farm in Louisina, supposedly with the PA deer yesterday, said he would like to talk. called today and spoke with Donald Hodge Jr. today on his Dads farm. his Dad just passed recently. it seems that several deer from Pennsylvania CWD exposed herd, or cohorts, were brought to Louisiana via Donald Hodge Sr. 6 deer were transported from PA to LA by Mr. Elmer Fisher, and the truck driver was Dustin Miller. here is where the story gets a bit tricky. seems there are NO records of the deer actually ever arriving at Donald Hodge Sr.’s Farm. seems that they were suppose to go to Lafayette Louisiana, but, seems he had a silent partner, a Jarrod somebody? the son was not sure. the son said that from his fathers notes (that’s all they had to go by), these 6 deer from PA never reached his farm, even though his Dad signed for them. the 6 deer were never logged into inventory, there were no tags, no micro chips from them found. the Dept. of Ag took soil samples. to date, the son said everything at his Dad’s farm is negative. now here is where the story gets even more fishy. the location changed from Lafayette Louisiana , to a location of an unregistered hunting club, or shooting pen, as he called it, and there was some attempted deal between the silent partner, and the delivery driver, to bring the 6 deer to this shooting pen in the area of Slidell Louisiana instead. the driver was offered $1,000. to take the deer there. but he refused, so evidently, the silent partner set up a meeting place, where another trailer was brought in, and the deer were then boxed up, and sent to this shooting pen up around Slidell Louisiana, somewhere along the Mississippi border. that is where the trail runs cold for these 6 deer from PA. the Donald Hodge Farm in LA, has about 160 cervids. NONE have been slaughtered or tested to date, and are being fed, and they are under quarantine. seems in Louisiana, there are no requirements for IN STATE movement of cervids from what Jr. told me. Donald Jr. told me the Dept. of Ag says there are two options if these 6 deer are not located. 1. kill the whole herd 2. Quarantine for 5 years. Donald Jr. told me he could not afford to quarantine for 5 years. seems right now, everything is in a holding pattern by the Dept of Ag, until they can locate the 6 deer from PA. the Son told me that he was told there is NO indemnity program if they slaughter the deer. It’s really a sad situation. Donald Hodge Sr., died Oct. 16 in a hunting accident, and Oct. 17 his farm was quarantined, and the family is beside themselves to say the least, as you can understand. kind regards, terry PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO LOUISIANA Got a private email. snip...as follows ; I would pass along a story. Nothing official has come out, but I have inside sources with multiple federal and state agencies in LA. But a deer or multiple deer, not sure which, from a CWD positive pen in PA was moved to a pen somewhere around Lake Charles, LA. The deer may have been moved to at least one other pen in LA, and possible one in MS as well, but no one really knows. There are supposedly 150 deer at the pen in Lake Charles that were quarentined and killed and they are now trying to figure out how and where to dispose of the carcasses. Everything is very sketchy and grey right now, but it is now possible that CWD could have spread to 1 or 2 more states. We shall see in the next few weeks if any kind of official press release comes out...end Read more: www.pfsc.proboards.com/index.cgi?action=display&board=disease&thread=583&page=1#ixzz2CDyJGlfYwww.pfsc.proboards.com/index.cgi?action=display&board=disease&thread=583&page=1 so, I gave the Pa dept of ag a call. this is the kind reply I got. ...tss From: xxxxxxxxx xxxxxx Sent: Wednesday, November 14, 2012 4:03 PM To: 'Flounder9@verizon.net' Subject: Deer information Terry - The animal moved on a certificate of veterinary inspection prior to the discovery of the positive CWD herd in Pennsylvania. Louisiana animal health authorities are investigating the movement of this deer that was epidemiologically linked to the index Pennsylvania herd, into their state. We are awaiting their response. Since the announcement of CWD positives in Pennsylvania there are no states permitting the movement of imported Pennsylvania deer and the Department of Agriculture is not permitting the movement of any deer into the commonwealth. -xxxxxx snip... Pennsylvania Department of Agriculture | Press Office 2301 North Cameron Street | Hbg PA 17110 Phone: 717.787.5085 | Fax: 717.787.1039 www.agriculture.state.pa.us ==================== I thank the Dept of Penn Ag for that kind reply and information. I pray that CWD has not been transported to Louisiana from Pennsylvania, via the great escape of CWD 2012 into Pennsylvania from captive game farming. ...tss Tuesday, November 13, 2012 PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD chronic-wasting-disease.blogspot.com/2012/11/pennsylvania-2012-great-escape-of-cwd.html TSS Wednesday, November 14, 2012 PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO LOUISIANA chronic-wasting-disease.blogspot.com/2012/11/pennsylvania-2012-great-escape-of-cwd_14.html
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Post by melody on Nov 15, 2012 13:58:25 GMT -5
Chronic Wasting Disease -- Pa.’s Agriculture Department a disappointmentBy Mark Nale Posted on November 9, 2012 www.outdoornews.com/November-2012/Chronic-Wasting-Disease-Pas-Agriculture-Department-a-disappointment/Chronic wasting disease is now within Pennsylvania’s borders. With CWD already in New York, Maryland and West Virginia, Pennsylvania Game Commission Executive Director Carl Roe shared his concern with me last Monday. “It wasn’t a matter of ‘if,’ but rather, ‘when’ CWD would get here.” The “when” occurred about a month ago, when the first case of CWD was confirmed in a captive doe that died in Adams County. Since then, a second deer -- a buck -- from the same quarantined farm in New Oxford, Pa., has tested positive for CWD. Three other facilities in three counties have also been quarantined since early October, because the sick deer had passed through all of them. Subsequently, the Pennsylvania Department of Agriculture pinpointed at least 25 additional deer farms in the Keystone State that received deer from one of the original four farms identified in October. The quarantine list grows almost daily and now involves deer farms in 16 counties. Some deer had even been sold out-of-state. Unfortunately, our infection with CWD follows a similar pattern to what has occurred in many other states -- this disease was first discovered in a captive deer. Pennsylvania is home to about 1,100 deer and elk farmers -- some big operations, some small. The Pennsylvania Department of Agriculture is the controlling agency when it comes to captive deer raised by deer farmers. The Game Commission is in charge of wild deer. I am more than a little unhappy with the quality and quantity of effort from officials at the state Department of Agriculture. They botched the effort to euthanize (for CWD testing) the remaining nine deer at the New Oxford facility, with one doe escaping on Oct. 16. As of this writing, this possible CWD carrier is still on the loose. Another doe from the New Oxford farm was sold to Freedom Whitetails (Blair County) and then sold again to a deer farmer in Huntingdon County. It has also escaped. The suspect doe is wearing a purple ear tag with a number 4 on it and it has been loose -- possibly spreading CWD prions in its urine -- since early summer. Travis Rhodes, the owner of Freedom Whitetails, has offered a $200 reward to anyone who kills this doe. According to Rhodes, if it tests negative for CWD, his facility will be removed from the quarantine. Where is the oversight? To me, the ag department’s quarantine seems almost meaningless, because no one is watching. The department’s press secretary commented to me, “We trust that our deer farmers are being ethical about this.” My bank trusts that its customers are ethical, too. That is why they have a thick vault, security cameras and bulletproof glass at the drive-up window, and they ask for identification. Hunters would like to see the same level of concern from the Pennsylvania Department of Agriculture. Are we asking too much?
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Post by Deleted on Nov 15, 2012 16:08:52 GMT -5
Mel, is that Carl Roe saying he is unhappy with Ag's performance or is it you? If it was Carl, I am surprised and pleased he said it.
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Post by melody on Nov 15, 2012 16:57:51 GMT -5
The article was by Mark Nale. I'd say it is him sharing his displeasure of Ag's performance based on information (or lack there of) regarding the whole situation.
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Post by Deleted on Nov 15, 2012 17:25:39 GMT -5
OK thanks.
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Post by melody on Nov 30, 2012 17:54:04 GMT -5
York man, convicted felon allegedly poached deer in CWD areawww.abc27.com/story/20227216/pa-man-allegedly-poached-deer-in-cwd-areaBy Sari Heidenreich - email YORK, Pa. (WHTM) - Authorities say a central Pennsylvania man illegally killed three deer in an area with special hunting restrictions related to a deadly neurological disease. The state game commission says 28-year-old Michael Moffitt is also a convicted felon forbidden to possess a firearm who dragged the deer's carcass across a York County elementary school campus on Tuesday. Game Commission Spokesman Jerry Feaser said Moffitt is being charged with 20 counts of 13 different crimes, including one count of a felon not to possess a firearm, three counts of poaching, four counts of violating the executive order related to Chronic Wasting Disease and other crime and wildlife code violations. Read More: www.abc27.com/story/20227216/pa-man-allegedly-poached-deer-in-cwd-area
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Post by neville on Dec 7, 2012 6:44:46 GMT -5
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Post by flounder on Dec 7, 2012 10:46:15 GMT -5
question please, can Mr. Neville, or anyone, confirm or deny anything about this (see below) seems the only ones getting any information on all this are the captive shooting pen owners and the dept of ag. thanks...
"i was told today that Pa permits and Ny permits were starting to be done again. Looks like the borders will be open again and alot of states will still take in Pa whitetails."
"Permits in Ny has already been released. The only reason Ny slowed down was because of tracebacks. 4 farms in Ny were held up for a bit because they dealt with the home farm in Pa."
kind regards, terry
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