Inactivation of chronic wasting disease prions using sodium

[flounder]

FRIDAY, OCTOBER 04, 2019

Inactivation of chronic wasting disease prions using sodium hypochlorite

journals.plos.org/plosone/article?id=10.1371/journal.pone.0223659

chronic-wasting-disease.blogspot.com/2019/10/inactivation-of-chronic-wasting-disease.html

kind regards, terry

[GlennD]

So, a quick scan of the link implies cleaning your knives with bleach will inactivate CWD Prions. ??

[davet]

I'm having a difficult time with that link. I went to the link and there is a voluminous amount of information there.......but I can't tell if it's based upon actual scientific data.....or just a whole bunch of "stuff" that makes a simplistic conclusion from "stuff" with no test data from known sources.

All this time......"Bleach"...EH?

Seems to simple to be true.

[Deleted]

So, when you cut the skull plate off with the antlers, soak it in bleach, soak the saw you used and any knives you may have used for butchering, and if you grind your meat into hamburger, soak the grinding parts too.  That should do it, huh?

We have also come to the conclusion that what we will do if we kill a deer this year is to debone it, place it in a plastic bag labeled with the tag information and date, and freeze it.  We will be submiting all heads to the PGC for that free testing.  We will eat no venison until the information on a kill comes back that the testing was negative for CWD.

One suggestion I would like to make is this.  If a deer tests positive, the PGC could give that hunter a voucher for a free tag next year?  Any thoughts?

[CoureurDeBois]

I like the idea of the free tag. I would want a choice for the tag though, either a current one or one for next year. Depending when the deer was harvested, or when the results came back would determine which year I would want the tag for. If I kill a deer say tomorrow, and the test comes back next week positive I would want a new tag now. If the same thing happened in the rifle or flintlock season then I would want that tag for next year.
Also like your plan on deboning the meat and freezing till the test come back.

[CoureurDeBois]

Might not be a bad idea to soak your gutting knife after each use also. Would be easy to do once you returned to home or camp.

[davet]

Heavy duty latex gloves may be a good idea this year as well. Can't hurt.

[flounder]

i think some hunters that don't read this carefully are going to thing this is a cure all for cwd tse contamination. IT'S NOT!

first off, it would take a strong bleach type sodium hypochlorite, that is NOT your moms bleach she uses in her clothes, and store bought stuff.

Concentrated bleach is an 8.25 percent solution of sodium hypochlorite, up from the “regular bleach” concentration of 5.25 percent.Nov 1, 2013 waterandhealth.org/disinfect/high-strength-bleach-2/

second off, the study states plainly;

''We found that a five-minute treatment with a 40% dilution of household bleach was effective at inactivating CWD seeding activity from stainless-steel wires and CWD-infected brain homogenates. However, bleach was not able to inactivate CWD seeding activity from solid tissues in our studies.''

''We initially tested brains from two CWD-infected mice and one uninfected mouse using 40% bleach for 5 minutes. The results from these experiments showed almost no elimination of prion seeding activity (Table 4). We then increased the treatment time to 30 minutes and tested 40% and 100% bleach treatments. Again, the results were disappointing and showed less than a 10-fold decrease in CWD-seeding activity (Table 4). Clearly, bleach is not able to inactivate prions effectively from small brain pieces under the conditions tested here.''

''We found that both the concentration of bleach and the time of treatment are critical for inactivation of CWD prions. A 40% bleach treatment for 5 minutes successfully eliminated detectable prion seeding activity from both CWD-positive brain homogenate and stainless-steel wires bound with CWD. However, even small solid pieces of CWD-infected brain were not successfully decontaminated with the use of bleach.''

journals.plos.org/plosone/article?id=10.1371/journal.pone.0223659

chronic-wasting-disease.blogspot.com/2019/10/inactivation-of-chronic-wasting-disease.html

i think with all the fear from recent studies, and there are many, of potential, or likelihood of zoonosis, if it has not already happened as scjd, i think this study came out to help out on some of that fear, that maybe something will help, but the study plainly states it's for sure not a cure all for exposure and contamination of the cwd tse prion on surface materials. imo...terry

[GlennD]

SO, I suppose we should go back to only eating Food Lion bleached meat?